手术时长、术中出血量及年龄与LFOR手术患者发生院内感染的关系研究

Relationship between operation time,intraoperative blood loss,age and nosocomial infection of patients undergoing surgery in LFOR

目的分析手术时长、术中出血量及年龄与层流手术室(LFOR)手术患者发生院内感染的关系。方法回顾性选择2017年10月至2019年10月池州市人民医院LFOR手术患者1080例为研究对象,统计LFOR手术患者院内感染情况,采用单因素和多因素logistic回归分析LFOR手术患者院内感染的影响因素,采用Spearman相关分析LFOR手术患者院内感染与各因素的相关性。结果1080例LFOR手术患者发生院内感染41例(3.80%)。性别、体重指数、合并糖尿病情况、合并高血压情况、麻醉方式、手术室平均人次、手术切口分类、手术类型不同的LFOR手术患者院内感染率差异无统计学意义(P>0.05);年龄≥60岁的LFOR手术患者院内感染率显著高于年龄<60岁的LFOR手术患者(P<0.05);手术时长≥2 h的LFOR手术患者院内感染率显著高于手术时长<2 h的LFOR手术患者(P<0.05);术中输血的LFOR手术患者院内感染率显著高于术中未输血的LFOR手术患者(P<0.05);年龄≥60岁、手术时长≥2 h、术中输血是LFOR手术患者院内感染的危险因素(P<0.05);LFOR手术患者院内感染与性别、体重指数、合并糖尿病情况、合并高血压情况、麻醉方式、手术室平均人次、手术切口分类、手术类型无相关性(P>0.05),与年龄、手术时长、术中输血呈正相关(P<0.05)。结论年龄≥60岁、手术时长≥2 h、术中输血是LFOR手术患者院内感染的危险因素,临床应对此类患者加以关注并严密把控,以降低LFOR手术患者院内感染发生率,使患者术后迅速恢复。

Objective To investigate the relationship between operation time,intraoperative blood loss,age and nosocomial infection of patients in laminar flow operating room(LFOR).Methods 1080 patients underwent surgery in LFOR in Chizhou People's Hospital from October 2017 to October 2019 were enrolled,and the incidence rate of nosocomial infection was recorded.Univariate and multivariate logistic regression were used to analyze the influencing factors of nosocomial infection,and spearman correlation was used to analyze the correlation between nosocomial infection and various factors.Results Nosocomial infection occurred in 41 of 1080 LFOR patients(3.80%).Nosocomial infection rate had no significant difference among LFOR patients with different gender,body mass index,diabetes mellitus,hypertension,anesthesia mode,average personnel movement in operating room,classification of surgical incision,and operation type(P>0.05).The nosocomial infection rate of LFOR patients aged≥60 years was significantly higher than that of LFOR patients aged<60 years(P<0.05).The nosocomial infection rate of LFOR patients with operation time≥2 h was significantly higher than that of LFOR patients with operation time<2 h(P<0.05).The nosocomial infection rate of intraoperative transfusion LFOR patients was significantly higher than that of patients without intraoperative transfusion(P<0.05).Age≥60 years,operation time≥2 h,and intraoperative blood transfusion were risk factors for nosocomial infection in LFOR patients(P<0.05).Nosocomial infection of LFOR patients was not correlated with gender,body mass index,diabetes mellitus,hypertension,anesthesia mode,average personnel movement in operating room,classification of surgical incision and operation type(P>0.05),while was positively correlated with age,length of operation,and intraoperative blood transfusion(P<0.05).Conclusion Age≥60 years,surgical duration≥2 h,and intraoperative blood transfusion are risk factors for nosocomial infection in patients undergoing surgery in LFOR.Risk groups should be closely controlled clinically,so as to reduce the incidence of nosocomial infection in patients undergoing surgery in LFOR and enable the postoperative recovery.