肺炎支原体肺炎患儿机体免疫细胞功能变化研究

Study on the changes of immune cell function in children with Mycoplasmal pneumoniae pneumonia

目的观察肺炎支原体肺炎(MPP)患儿机体免疫细胞功能的变化。方法将31例MPP患儿分为急性期组(n=14)和恢复期组(n=17)。比较2组免疫细胞功能与相关指标(CD3^+、CD4^+和CD4^+/CD8^+、CD19、CD56)水平的变化。结果急性期组的CD3^+、CD4^+、CD4^+/CD8^+、CD19和CD56的表达水平均低于恢复期组,差异有统计学意义(P <0.05)。结论检测MPP患儿机体免疫细胞功能相关指标,可有效评估病情,提高疾病治愈率。

Objective To observe the changes of immune cell function in children with Mycoplasmal pneumoniae pneumonia(MPP).Methods Thirty-one children with MPP were divided into the acute stage group(n=14)and the convalescent stage group(n=17).The changes of immune cell function and related indicators(CD3^+,CD4^+,CD4^+/CD8^+,CD19 and CD56)were compared in the two groups.Results The expression levels of CD3^+,CD4^+,CD4^+/CD8^+,CD19 and CD56 in the acute stage group were all lower than those in the recovery stage group,and the differences were statistically significant(P<0.05).Conclusion Detection of immune cell function related indicators in MPP children can effectively evaluate the disease condition and improve the cure rate.