乳果糖在胶囊内镜检查时肠道准备中的应用价值

Application Value of Lactulose in Intestinal Preparation During Capsule Endoscopy

目的探讨胶囊内镜检查中应用乳果糖进行肠道准备的临床应用价值。方法选取我院消化内科拟实施胃肠道胶囊内镜检查的患者200例作为研究对象,采用随机数字分为A组和B组各100例,A组采用磷酸钠盐口服液进行肠道准备,B组采用磷酸钠盐+乳果糖进行肠道准备;对比两组的肠道清洁度,胶囊通过胃、小肠的时间,两种肠道准备方法患者的耐受情况。结果B组患者的小肠、结肠肠道清洁评分分级均优于A组患者,差异有统计学意义(P<0.05);B组患者胶囊内镜通过小肠、胃的时间均短于A组患者,差异有统计学意义(P<0.05);B组患者不良反应发生率4.00%低于A组患者的12.00%,差异有统计学意义(P<0.05)。结论胶囊内镜检查中磷酸钠盐+乳果糖进行肠道准备较单用磷酸钠盐口服液具有更好的肠道清洁效果,缩短内镜在体内的运行时间,降低不良反应发生率。

Objective To explore clinical application value of lactulose for bowel preparation in capsule endoscopy.Methods 200 patients who undergo gastrointestinal capsule endoscopy in our hospital were selected as research object.They were divided into group A(n=100)and group B(n=100)by using random numbers.For bowel preparation,group A used sodium phosphate oral solution,while group B used sodium phosphate+lactulose.Intestinal cleanliness,time of capsule passed through stomach and small intestine,and tolerance were compared.Results Cleansing scores of small intestine and colon intestinal in group B were better than those of group A with statistically significant difference(P<0.05).Time of capsule endoscopy through small intestine and stomach of group B was shorter than that of group A,with statistically significant difference(P<0.05).Incidence of adverse reactionsin group B(4.00%)was lower than in group A(12.00%)with statistically significant difference(P<0.05).Conclusion In capsule endoscopy,sodium phosphate+lactulose for bowel preparation has bettercleaning effectthan sodium phosphate oral solution alone,which could shorten running time of endoscope in bodyand reduce incidence of adverse reactions.