摘要
恢复三级侧支循环、促进血管新生是脑梗死防治的重要切入点。在前期理论研究基础上结合血管新生中血管内皮细胞增殖、迁移、分化的微观现象,提出荣气虚滞是脑梗死后血管新生不足的理论基础。荣气气化的"精化气-气生变-变成形"过程能针对性启动或促进脑梗死内源性血管新生,在荣气理论指导下的活血荣络方能促进血管新生,从而具有较好的防治脑梗死作用。
Restoring tertiary collateral circulation and promoting angiogenesis is an important starting point for the prevention and treatment of cerebral infraction.Based on the previous theoretical research,combined with the microscopic phenomena of vascular endothelial cell proliferation,migration and differentiation in angiogenesis,it is proposed that the deficiency and stagnation of Rong Qi is the theoretical basis of insufficient angiogenesis after cerebral infarction.The process of transformation of Rong Qi"essence transforming into Qi-Qi generating change-change into form"can specifically initiate or promote endogenous angiogenesis in cerebral infarction,and is demonstrated from the perspective of clinical efficacy and modern pharmacology.Under the guidance of Rong Qi theory,Huoxue Rongluo Formula based on the method of activating blood circulation and nourishing collaterals can promote angiogenesis and has a better effect on preventing and treating cerebral infarction.
作者
杨仁义
周德生
傅馨莹
颜思阳
谭惠中
蔡昱哲
刘利娟
YANG Renyi;ZHOU Desheng;FU Xinying;YAN Siyang;TAN Huizhong;CAI Yuzhe;LIU Lijuan(Hunan University of Chinese Medicine,Changsha,Hunan 410208,China;The First Hospital of Hunan University of Chinese Medicine,Changsha,Hunan 410007,China)
出处
《湖南中医药大学学报》
CAS
2020年第12期1562-1566,共5页
Journal of Hunan University of Chinese Medicine
基金
国家中医药管理局全国名老中医药专家传承工作室(国中医药人教发〔2014〕20号)
国家自然科学基金资助项目(81874463)
湖南省科技厅科技创新平台与人才计划(2017SK4005)
湖南省财政中医药项目名院工程院内优势病种项目(rsk-010-013/006-09)
湖南省中医药管理局资助项目(201824,202046,202038)
湖南省教育厅资助项目(20C1405)
湖南省研究生创新项目(CX20190587)
湖南中医药大学中西医结合一流学科开放基金项目(2019ZXYJH08,2018ZXYJH10)
湖南中医药大学研究生培养质量工程专项(2020CX62)。
关键词
脑梗死
荣气理论
血管新生
活血荣络
缺血中风
cerebral infarction
Rong Qi theory
angiogenesis
activating blood circulation and nourishing collaterals
ischemic stroke
