摘要
通过调研近年来中医药治疗胃溃疡相关研究资料,系统梳理胃溃疡动物模型、中医药治疗胃溃疡的实验研究进展。中医药在中医辨证指导下治疗胃溃疡具有独特优势和广阔应用前景。目前中医药的胃溃疡研究仍以实验性胃溃疡动物模型为主,缺少中医药特点;病证结合模型评价体系不完善,研究深度不够,机制间缺少相互作用联系。本文对胃溃疡中医药治疗研究进展进行综述,以期为胃溃疡的临床治疗及药物开发提供参考。
This article reviewed the research literature of Traditional Chinese medicine treating gastric ulcer in recent years,we systematically studied gastric ulcer animal models and experimental studies of TCM treating gastric ulcer.Under the guidance of syndrome differentiation,TCM has unique advantages and wide application prospects in the treatment of gastric ulcer.At present,the research of TCM on gastric ulcer is still based on traditional animal models,but which lacked the characteristics of TCM.The evaluation system of the animal model which combined the etiology with the syndrome is imperfect,and the further study on the interaction between mechanisms is needed.This article reviewed the research progress of TCM in the treatment of gastric ulcer,in order to provide reference for the clinical treatment and drug development of gastric ulcer.
作者
魏广义
刘楠楠
王淑美
孔令雷
杜冠华
Wei Guangyi;Liu Nannan;Wang Shumei;Kong Linglei;Du Guanhua(Guangdong pharmaceutical University,Guangzhou 51006;Beijing Key Laboratory of Drug Targets Identification and Drug Screening,Institute of Materia Medica,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100050)
出处
《中药药理与临床》
CAS
CSCD
北大核心
2020年第5期228-232,共5页
Pharmacology and Clinics of Chinese Materia Medica
基金
“新药创制”科技重大专项(编号:2018ZX09711001-009-009)
中国医学科学院医学与健康科技创新工程(编号:2016-I2M-3-007、2017-I2M-1-010)
北京市自然科学基金面上项目(编号:7182113)
国家重点研发计划(编号:2016YFC1000905)。
关键词
胃溃疡
中药
动物模型
作用机制
Gastric ulcer
Traditional Chinese Medicine
animal models
pharmacology mechanism