摘要
精神分裂症的临床治疗以抗精神病药全程治疗为主,遗传因素显著影响药物疗效和不良反应的个体差异。随着分子遗传学研究进展,药物遗传学在精神分裂症精准医疗中将发挥日益重要的作用。
The clinical treatment of schizophrenia is based on the long-term treatment of antipsychotics,and genetic factors significantly affect the individual differences in therapeutic efficacy and side effects.With the progress of molecular genetics,pharmacogenomics may play an increasingly important role in precision medicine for schizophrenia.
作者
岳伟华
王强
Yue Weihua;Wang Qiang(Peking University Sixth Hospital,Institute of Mental Health,National Clinical Research Center for Mental Disorders&Key Laboratory of Mental Health,Ministry of Health(Peking University)&Chinese Academy of Medical Sciences Research Unit(No.2018RU006),Beijing 100191,China;Mental Health Center,West China Hospital of Sichuan University,Chengdu 610041,China)
出处
《中华精神科杂志》
CAS
CSCD
北大核心
2020年第6期469-472,共4页
Chinese Journal of Psychiatry
基金
国家重点研发计划(2016YFC1307000)
国家科技重大专项重大新药创新(2018ZX09201-014)。
关键词
精神分裂症
遗传药理学
精准医疗
Schizophrenia
Pharmacogenetics
Precision medicine
