神经梅毒在卒中单元中的临床特点

Clinical features of neurosyphilis in stoke unit

目的探讨卒中单元中神经梅毒(NS)的临床特点。方法回顾性分析在2016年1月至2018年12月入住常熟市第二人民医院卒中单元中患者的梅毒学检查及NS患者的临床资料。结果2385例患者接受了梅毒学检查,所有接受梅毒学检查患者中,血梅毒抗体明胶凝集试验(TPPA)阳性为2.05%(49例),血浆快速反应素试验(RPR)阳性为0.88%(21例)。进行脑脊液(CSF)检查为0.92%(22例),最终确诊NS12例,占进行CSF检查患者的54.55%,12例NS患者经过治疗病情好转。结论梅毒学检查应该作为卒中单元中患者的常规检查,对有阳性发现的患者积极进行CSF检查,尽早确诊治疗。

Objective To analyze clinical manifestation of the patients with neurosyphilis in stroke unit.Methods The clinical and experimental test of syphilis data of neurosyphilis patients treated in the stroke unit of Changshu No.2 people’s hospital during 2016-2018 were retrospectively analyzed.Results 2385 patients underwent experimental test of syphilis.2.05%(49 cases)were treponema pallidum particle agglutination assay(TPPA)positive,and 0.88%(21 cases)were rapid plasma reagin assay(RPR)positive.The cerebrospinal fluid(CSF)of 22 patients(0.92%)was investigated,among which 12 cases(54.55%)were diagnosed as neurosyphilis.NS patients became better after receiving anti-syphilitic treatments.Conclusion Syphilitic examination should be a routine test for the patients in the stroke unit.Positive detection of the patients should receive cerebrospinal fluid examination and be treated early.