小剂量右美托咪定静脉泵注联合丙泊酚对宫腔镜手术的麻醉作用

Anesthetic Effect of Low Dose Dexmedetomidine and Propofol on Hysteroscopic Surgery

目的分析小剂量右美托咪定静脉泵注联合丙泊酚对宫腔镜手术的麻醉作用。方法选取60例宫腔镜手术患者作为观察对象,分为试验组和对照组,每组各30例。对照组术前静脉泵注1μg/kg的右美托咪定,试验组术前静脉泵注0.5μg/kg的右美托咪定。对比两组患者麻醉即刻和手术结束即刻的血流动力学指标(平均动脉压、心率)、麻醉前后的OAA/S镇静警觉评分、清醒时间和不良反应发生率。结果试验组患者的麻醉即刻和手术结束即刻的血流动力学指标均明显好于对照组,试验组患者麻醉后的镇静警觉评分更高、清醒时间更短,术后嗜睡的发生率明显低于对照组(P<0.05)。结论小剂量右美托咪定静脉泵注联合丙泊酚对宫腔镜手术的麻醉作用突出,有利于手术的顺利、安全开展,且不良反应的发生率更低,值得临床推广应用。

Objective To explore the anesthetic eff ect of small dose dexmedetomidine combined with propofol on hysteroscopic surgery.Methods Sixty patients undergoing hysteroscopy surgery were selected as observation objects and divided into an experimental group and a control group,with 30 cases in each group.The control group was given 1μg/kg dexmedetomidine intravenously before operation,while the experimental group was given 0.5μg/kg dexmedetomidine.The hemodynamic indicators(mean arterial pressure,heart rate),OAA/S sedation alert score before and after anesthesia,time to wake up,and incidence of adverse reactions were compared between the two groups immediately after anesthesia and at the end of operation.Results The hemodynamic indicators of the patients in the experimental group immediately after anesthesia and immediately after the operation were signifi cantly better than those in the control group.The patients in the experimental group had a higher sedation alert score and shorter awake time after anesthesia,and the incidence of postoperative sleepiness was signifi cantly lower in the control group(P<0.05).Conclusion Low dose dexmedetomidine intravenous pump combined with propofol has a prominent anesthetic eff ect on hysteroscopic surgery,which is conducive to the smooth and safe operation,and the incidence of adverse reactions is lower,which is worthy of clinical application.