摘要
To break through the size limitation in DNA structure assembly and to achieve the construction of DNA structures with submicrometre and micrometre scale,Fan and Yan et al.proposed a versatile DNA structure assembly strategy,named as meta-DNA(M-DNA)strategy.Submicrometre-sized M-DNA,which has a six-helix bundle DNA origami nanostructure,is used as building block to precisely assemble a series of submicrometre-to-micrometre-sized DNA architectures with customed shapes,including meta-multi-arm junctions,polyhedrons and closely packed lattices.Besides static assembly,the proposed M-DNA strategy was also demonstrated to work well for the programmed dynamic rearrangement of DNA structures.This work has been published online in the Nature Chemistry on September 7,2020.
