SARS-CoV-2感染者的早期实验室指标分析

Analysis of early determination indicators for SARS-CoV-2 Infection

目的探讨严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染者早期实验室指标特征,为早期鉴别SARS-CoV-2感染者提供参考依据。方法将已确诊的21例SARS-CoV-2感染者作为感染组,将24例已排除SARS-CoV-2感染的疑似患者作为对照组,比较2个组的早期实验室指标。结果2个组白细胞计数、中性粒细胞绝对数、淋巴细胞绝对数、单核细胞绝对数、嗜酸性粒细胞绝对数、嗜碱性粒细胞绝对数、C反应蛋白(CRP)、降钙素原(PCT)、D-二聚体(DD)、纤维蛋白原(Fib)、肌酸激酶(CK)、羟丁酸脱氢酶(HBDH)、红细胞沉降率(ESR)差异均无统计学意义(P>0.05)。结论SARS-CoV-2感染者临床表现不典型,以上实验室指标不能用于对早期SARS-CoV-2感染者的鉴别。

Objective To investigate the characteristics of early determination indicator results for severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection,and to provide a reference for the early identification of SARS-CoV-2 infection.Methods There were 21 cases of SARS-CoV-2 infection and 24 cases excluding SARSCoV-2 infection.Their determination indicator results in the early stage were compared.Results There was no statistical significance in white blood cell count,neutrophil count,lymphocyte count,monocyte count,eosnophil count,basophil count,C-reactive protein(CRP),procalcitonin(PCT),D-dimer(DD),fibrinogen(Fib),creatine kinase(CK),hydroxybutyrate dehydrogenase(HBDH)and erythrocyte sedimentation rate(ESR)between the 2 groups(P>0.05).Conclusions The clinical manifestations of SARS-CoV-2 infection are atypical,and all these determination indicators can not be used in identify SARS-CoV-2 infection in early stage.