摘要
以N-异丙基丙烯酰胺为温敏单体,丙烯酸为功能单体,甲基丙烯酸羟乙酯为辅助功能单体,制备出了氧氟沙星印迹的pH/温度双敏感水凝胶,并将该材料用于水中氧氟沙星的检测过程中。考察了水凝胶的温度和pH敏感性对氧氟沙星吸附与洗脱的影响,结果显示材料对氧氟沙星具有很好的选择性分离与富集效果,回收率可达90%以上,相对标准偏差小于2%。
A pH/temperature double-responsive imprinted hydrogels were successfully prepared in the presence of thermosensitive monomer(N-isopropylacrylamide),functional monomer(acrylic acid),auxiliary functional monomer(hydroxyethyl methacrylate)and template molecule(ofloxacin).The material was applied to the detection of ofloxacin in water and the effects of temperature and pH sensitivity of hydrogel on the adsorption and elution of ofloxacin were investigated.The results showed that the material had good selective separation and enrichment effect on ofloxacin,and the enrichment recovery was over 90%and the relative standard deviation was less than 2%.
作者
蒋彩云
刘家勋
吴婷
周海飞
王玉萍
JIANG Cai-yun;LIU Jia-xun;WU Ting;ZhOU Hai-fei;WANG Yu-ping(School of Health,Jiangsu Vocational Institute of Commerce,Jiangsu Engineering and Research Center of Food Safety,Nanjing 211168,China;College of Chemistry and Materials Science,Nanjing Normal University,Nanjing 210097,China)
出处
《化学研究与应用》
CAS
CSCD
北大核心
2020年第12期2139-2147,共9页
Chemical Research and Application
基金
国家自然科学基金项目(51578295)资助
江苏省自然科学基金项目(BK20161479)资助
江苏省青蓝工程项目资助
江苏经贸职业技术学院重大课题(JSJM19002)资助。
关键词
智能凝胶
分子印迹
氧氟沙星
富集
intelligent hydrogel
molecularly imprinted
ofloxacin
enrichment