口腔幽门螺杆菌感染与种植体周围炎及其临床指标的相关性分析

Correlation Analysis of Oral Helicobacter pylori Infection with Peri-implantitis and Its Clinical Parameters

目的比较种植体周围炎患者与非种植体周围炎患者种植位点龈下口腔幽门螺杆菌阳性率的差异,并进一步分析口腔幽门螺杆菌感染与种植体周围炎3项典型临床指标的相关性。方法对随访的67例种植体周围炎患者和63例非种植体周围炎患者的种植位点进行检测。收集微生物样本,采用聚合酶链反应法检测幽门螺杆菌,并记录探诊深度、探诊出血和溢脓等临床指标,统计分析口腔幽门螺杆菌感染与种植体周围炎及典型临床指标的相关性。结果种植体周围炎组幽门螺杆菌的阳性率为59.70%,显著高于非种植体周围炎组的41.27%。此外,口腔幽门螺杆菌阳性率与探诊出血、探诊深度增加和溢脓这3项临床指标也有显著相关性。结论口腔幽门螺杆菌感染可增加种植体周围感染的危险性。

Objective To investigate the difference in Helicobacter pylori(H.pylori)infection rate between peri-implantitis patients and healthy implant group,and relationship between clinical indicators of peri-implantitis and H.pylori infection.Methods Sixty-seven patients with peri-implantitis and 63 healthy implant controls were included in this study.Clinical parameters including probing depth,bleeding on probing,and suppuration were recorded.Microbiological samples were collected and polymerase chain reaction was used to detect H.pylori.Correlations between H.pylori infection and peri-implantitis and associated clinical parameters were statistically analyzed.Results In the peri-implantitis group,the H.pylori positive rate(59.70%)was significantly higher than that in the healthy implant group(41.27%).There was a significant relationship between H.pylori positive rate and principal clinical indicators of peri-implantitis.Conclusion H.pylori infection may increase the risk of peri-implantitis.