简述胃肠动力调节机制的研究进展

Progress in research of gastrointestinal motility regulation

胃肠动力是消化道生理功能的重要组成部分,其功能紊乱是引起多种胃肠动力障碍疾病的关键因素之一.这些疾病严重影响人们的正常生活.随着科研技术的发展,人们对胃肠动力调节机制方面的研究越来越多,其作用机制主要涉及对胃肠激素、肠道菌群、胃肠道神经递质、脑—肠肽、Cajal间质细胞和胃肠电活动的调节等.除此之外,很多研究发现苦味及其受体对胃肠运动有一定的调节作用.该文章主要简述了几种调节胃肠动力的机制研究进展.

Gastrointestinal motility is an important part of the physiological function of the digestive tract,and its dysfunction is one of the key factors that cause different gastrointestinal motility disorders.These diseases seriously affect patients’normal life.With the development of scientific research and technology,well-designed research studies have been conducted on the regulatory mechanisms of gastrointestinal motility,which mainly include the regulation of gastrointestinal hormones,intestinal microflora,neurotransmitters,brain-gut peptides,interstitial cells of Cajal,and gastrointestinal electrical activities.In addition,current studies have proved that bitter taste receptors have certain regulatory effects on gastrointestinal motility.This paper primarily discusses the relevant pathways controlling gastrointestinal motility.