泪道探通术联合妥布霉素滴眼液治疗先天性泪囊炎

Lacrimal duct probing combined with tobramycin eye drops in the treatment of congenital dacryocystitis

目的:探讨泪道探通术联合妥布霉素滴眼液治疗先天性泪囊炎的临床疗效。方法:选取2017-01/2019-06来我院就诊的先天性泪囊炎患儿228例250眼作为研究对象,年龄为6月龄~3岁。按年龄分为3组:6月龄~<1岁133例149眼,1~<2岁62例64眼,2~3岁33例37眼。三组均实施表面麻醉下泪道探通术联合术后妥布霉素滴眼液治疗。结果:先天性泪囊炎患儿中6月龄~<1岁治愈率为97.3%(145/149),1~<2岁治愈率为92.2%(59/64),2~3岁治愈率为83.8%(31/37),无不良事件发生。三组患儿治愈率比较,6月龄~<1岁患儿治愈率最高(P=0.009)。结论:泪道探通术治疗先天性泪囊炎疗效显著,术后联合妥布霉素滴眼液安全可靠。以6月龄~1岁为最佳治疗时机,其手术操作简单,并发症少,具有较高的临床价值。

AIM:To explore the clinical efficacy of probing lacrimal passage combined with tobramycin eye drops in the treatment of congenital dacryocystitis.METHODS:A total of 228 children(250 eyes)aged from 6mo-3a with congenital dacryocystitis treated in our hospital from January 2017 to June 2019 were included.They were assigned into three groups by age:133 patients(149 eyes)aged from 6mo-1a(Group A),62 patients(64 eyes)aged from 1-2a(Group B),and 33 patients(37 eyes)aged from 2-3a(Group C).All patients received lacrimal duct probing in surface anesthesia combined with postoperative tobramycin eye drops.RESULTS:The probing cure rates of congenital dacryocystitis among there groups were 97.3%(Group A),92.2%(Group B)and 83.8%(Group C),respectively.No adverse events reported.Through comparison of these three groups,the cure rate of children from 6mo-1a was the highest.The difference was statistically significant(P=0.009).CONCLUSION:Lacrimal duct probing is effective in the treatment of congenital dacryocystitis,and it is safe and reliable to combine tobramycin eye drops(TOBREX)after surgery.The best time for treatment is 6mo-1a.The operation is simple,less complication,with high clinical value.