摘要
Charged particle radiation is known to be more biologically effective than photon radiation.One example of this is the damage of human blood vessels,and this effect is an important factor influencing human health and is relevant to space travel as well as to cancer radiotherapy.Therefore,research on the protection endothelial cells from heavy ions radiation damage is of great significance.Studies showed that beta-D-glucan is one of the potential radioprotectors[1],but most of the studies were focused on the protection of beta-glucan on the immune and hematopoietic after X-/-rays irradiation.In the present study,we chose human umbilical endothelial cell line EA.hy926 as a model system to investigate the protective effect of beta-D-glucan on the injury induced by high-LET carbon ions irradiation,and explore the possible mechanism of the action.
