艾灸治疗2型糖尿病认知功能减退疗效观察

Clinical observation on therapeutic effect of moxibustion on cognitive decline in type 2 diabetes mellitus

目的:观察艾灸对2型糖尿病认知功能减退患者认知功能的影响。方法:将47例2型糖尿病认知功能减退患者随机分为观察组(24例,脱落4例)和对照组(23例,脱落3例)。对照组予以常规降糖处理,观察组在对照组基础上,穴取百会、大椎、神庭,行化瘀通络灸治疗,隔日1次,4周为一疗程,共治疗3个疗程。观察两组患者治疗前后听觉词语学习测验(AVLT)、复杂图形测验(CFT)、蒙特利尔认知评估量表(MoCA)及连接试验量表(TMT-A)评分,并比较两组临床疗效。结果:观察组治疗后AVLT即时记忆评分、延迟记忆评分均高于治疗前及对照组(P<0.05)。观察组治疗后MoCA量表中视空间与执行功能、延迟记忆、注意力、定向力评分均高于治疗前及对照组(P<0.05)。观察组总有效率为85.0%(17/20),高于对照组的10.0%(2/20,P<0.05)。结论:化瘀通络灸对2型糖尿病认知功能减退有较好的治疗效果。

Objective To observe the effect of moxibustion on cognitive function in patients with cognitive decline of type 2 diabetes mellitus(T2DM). Methods A total of 47 patients with cognitive decline of T2 DM were randomized into an observation group(24 cases, 4 cases dropped off) and a control group(23 cases, 3 cases dropped off). Conventional hypoglycemic intervention was adopted in the control group. On the basis of the treatment in the control group, Huayu Tongluo moxibustion(moxibustion for removing stasis and clearing collaterals) was applied at Baihui(GV 20), Dazhui(GV 14), Shenting(GV 24), once every 2 days, 4 weeks were as one course, totally 3 courses were required. Before and after treatment, scores of auditory verbal learning test(AVLT), complex figure test(CFT), Montreal cognitive assessment(MoCA) and trail making test-A(TMT-A) were observed in the both groups, and the clinical effective rates were compared. Results After treatment, the scores of immediate memory and delayed memory of AVLT in the observation group were higher than those before treatment and those in the control group(P<0.05). After treatment, the scores of visual space and executive function, delayed memory, attention and orientation of MoCA in the observation group were higher than those before treatment and those in the control group(P<0.05). The effective rate was 85.0%(17/20) in the observation group, which was superior to 10.0%(2/20) in the control group(P<0.05). Conclusion Huayu Tongluo moxibustion has a definite effect on cognitive decline of type 2 diabetes mellitus.