摘要
宫颈癌是女性生殖系统常见的妇科肿瘤之一,近年发病率呈上升趋势,严重威胁女性健康。持续性高危型人乳头瘤病毒(HPV)感染与宫颈癌的发生密切相关,但自HPV感染发展为宫颈癌需要多年,因此预防性接种HPV疫苗尤为重要。HPV疫苗是利用基因重组技术合成的病毒样颗粒,目前全球已有3种预防性HPV疫苗获得批准并广泛使用,且疫苗覆盖年龄范围广泛,具有良好的安全性。HPV疫苗对预防宫颈癌、提高女性生活质量具有重要意义,随着HPV疫苗的推广及应用,将有更多女性远离宫颈癌困扰。
Cervical cancer is one of the most common gynecologic tumors in the female reproductive system.The incidence of cervical cancer has been increasing in recent years,which seriously threatens the health of women.Persistent high-risk human papilloma virus(HPV)infection is closely related to the occurrence of cervical cancer.However,the course of disease from HPV infection to cervical cancer often lasts for many years.Therefore,the preventive vaccination of HPV vaccine is particularly important.HPV vaccine is a virus-like particle synthesized by gene recombination technology.At present,three kinds of preventive HPV vaccines have been approved and widely used in the world,and the vaccines cover a wide range of ages and have good safety.HPV vaccine plays an important role in preventing cervical cancer and improving women′s quality of life.With the popularization and application of HPV vaccine,more women will be far away from cervical cancer.
作者
王建东
赵子怡
WANG Jiandong;ZHAO Ziyi(Department of Gynecology and Oncology,Beijing Obstetrics and Gynecology Hospital Affiliated to Capital Medical University,Beijing 100026,China)
出处
《医学综述》
2020年第24期4785-4787,4792,共4页
Medical Recapitulate
关键词
宫颈癌
人乳头瘤病毒
HPV疫苗
Cervical cancer
Human papilloma virus
HPV vaccine