逐瘀缩宫颗粒用于大月份药物流产后的疗效观察

Observation of the Curative Effect of Zhuyu Suogong Granules Used after Medical Abortion

目的:观察逐瘀缩宫颗粒用于8~12周妊娠药物流产后气虚血瘀证的临床疗效。方法:98例研究对象随机分为观察组(n=49),对照组(n=49)。两组均于胎囊、胎芽排出后常规予缩宫素,观察组加口服“逐瘀缩宫颗粒”免煎颗粒剂,连服7d;对照组不予其他药物干预。观察两组疗效。结果:观察组子宫出血量、出血时间少于对照组(P<0.05);清宫率8.2%低于对照组24.5%(P<0.05);盆腔感染率2.0%低于对照组12.2%(P<0.05);月经恢复时间(30.2±3.3)d短于对照组(38.7±6.1)d(P<0.05);两组均无明显不良反应。结论:8~12周妊娠药物流产后口服“逐瘀缩宫颗粒”,可减少出血量、缩短出血时间,降低清宫率及盆腔感染率,缩短月经复潮时间,且安全性良好。

Objective:To observe the clinical efficacy of"Zhuyu Suogong Granules"on Qi deficiency and blood stasis syndrome caused by medical abortion in 8-12 weeks of pregnancy.Method:98 cases were randomly divided into observation group(49 cases)and control group(49 cases).Both groups were routinely given oxytocin after the fetal sac and buds were discharged.The observation group was given"Zhuyu Suogong Granules"for 7 consecutive days;the control group was not treated with other drugs.The bleeding volume,bleeding time,Uterine cleaning surgery rate,pelvic infection rate and menstrual recovery time were observed in the two groups.Result:The bleeding volume and bleeding time of the observation group were less than those of the control group(P<0.05);the Uterine cleaning surgery rate was 8.2%in the observation group and 24.5%in the control group(P<0.05);the pelvic infection rate was 2.0%in the observation group and 12.2%in the control group(P<0.05);The menstrual recovery time was(30.2±3.3)days in the observation group and(38.7±6.1 days)in the control group(P<0.05);there were no obvious adverse reactions in both groups.Conclusion:After medical abortion in 8 to 12 weeks of pregnancy,oral administration of"Zhuyu Suogong Granules"can reduce the amount of bleeding,shorten the bleeding time,reduce the rate of uterine curettage and pelvic infection,and shorten the time of menstrual.