去氧孕烯炔雌醇对药物流产不全行清宫术子宫内膜的修复作用

Recovery effect of desogestrel and ethinylestradiol tablets on endometrum of women with medical abortion after uterine curettage

目的:探讨去氧孕烯炔雌醇对药物流产清宫术后子宫内膜修复作用。方法:选取本院因药物流产不全经宫腔镜行清宫术的100例为研究对象,使用随机数字表法分为两组各50例,观察组在术后给予口服去氧孕烯炔雌醇片,对照组不做处理。对比两组术后阴道出血、子宫复旧及并发症发生情况。结果:术后2周,观察组超声复查子宫内膜厚度(3.20±0.74mm)大于对照组(2.71±0.17mm),子宫横径值、子宫纵径值均小于对照组(P<0.05)。两组术后阴道流血时间≤10d,但观察组≤5d者占比(86.0%)高于对照组(50.0%),与平素月经比较术后阴道流血量量少者占比(80.0%)高于对照组(60.0%),月经恢复时间<30d占比(92.0%)高于对照组(72.0%),术后并发症总发生率(4.0%)低于对照组(26.0%)(均P<0.05)。结论:药物流产清宫术后口服去氧孕烯炔雌醇片可促进受术女性子宫内膜修复,缩短阴道出血时间,调节月经周期,降低宫腔粘连发生风险。

Objective:To investigate the effect of desogestrel and ethinylestradiol tablets on endometrial repair of women with medical abortion after uterine curettage.Methods:100 women with medical abortion after uterine curettage were randomly divided into two groups(50 cases in each group).The women in observation group were given oral deoxypregnene ethinylestradiol tablets,while the women in control group were not given treatment.Vaginal bleeding volume,uterine involution situation,and complications rate of women were compared between the two groups.Results:Two weeks after abortion,the endometrial thickness(3.20±0.74mm)of women in the observation group was significant higher than that(2.71±0.17mm)of women in the control group,but the uterine transverse diameter and longitudinal diameter of women in the observation group were significant lower(P<0.05).The time of vaginal bleeding after operation of women in both groups was less than 10 days,but the proportion of women with vaginal bleeding time≤5 days in the observation group(86.0%)was significant higher than that(50.0%)of women in the control group,the proportion of women with vaginal bleeding volume less than menstruation in the observation group(80.0%)was significant higher than that(60.0%)of women in the control group,the proportion of women with the time of menstruation recovery<30d in the observation group(92.0%)was significant higher than that(72.0%)of women in the control group,and the total incidence of postoperative complications of women in the observation group(4.0%)was significant lower than that(26.0%)of women in the control group(all P<0.05).Conclusion:Oral deoxypregnene ethinylestradiol tablets after uterine curettage can promote endometrial repair,shorten the time of vaginal bleeding,regulate menstrual cycle,and reduce the risk of uterine adhesions.