关注环境内分泌干扰物,保护妇女儿童健康

Concerns over environmental endocrine disrupting chemicals and protection for women and children’s health

环境中的化学物在我们日常生活中无处不在。其中环境内分泌干扰物(endocrine disrupting chemicals,EDCs)是一类具有干扰机体内源性激素特点的外源化学物,可增加众多健康风险。特别引人注意的是,动物实验已经证实EDCs具有生殖毒性,EDCs对于处在发育关键期和敏感期的胎儿、婴幼儿,以及孕妇等易感人群的危害作用更加不容忽视。尽管我们在了解EDCs对健康的危害性上取得了长足的进步,但如何全面评价其生殖健康的风险尚处于起步阶段。本文就未来研究需要进一步关注的方面进行综述,并提出相关建议。

Environmental chemicals are omnipresent in our daily life. Among them, endocrine disrupting chemicals(EDCs) are exogenous chemicals that interfere with hormone action, thereby increasing the risk of adverse health outcomes. As it has already been proved by numerous laboratory and epidemiology studies, EDCs have a profound and life-long impact on human reproduction, especially for those at critical and sensitive developmental stages such as fetuses, infants, children, and women in reproductive age. Despite we have made progress in acknowledging the adverse effects, it is still at the beginning stage to comprehensively evaluate the reproductive risks of EDCs. The purpose of this paper is to provide an overview of future research directions and some recommendations.