新烟碱类杀虫剂人群暴露水平及生殖毒性的研究进展

Research progress on human exposure levels and reproductive toxicity of neonicotinoids

新烟碱类杀虫剂是一种以烟碱结构为基础而研制的新型杀虫剂,对哺乳动物的毒性远低于传统杀虫剂,但仍可通过饮用水和食物链等途径在人体中富集,对健康产生一系列不良影响。因此,新烟碱类杀虫剂的潜在毒性引起了人们的关注。然而相关人体生殖毒性的研究较少。本文综述了新烟碱类杀虫剂的国内外人群暴露情况、生殖毒性及其相关作用机制,为今后深入探讨新烟碱类杀虫剂的人体生殖毒性提供方向。

Neonicotinoid insecticides are emerging pesticides based on the nicotine structure. Although neonicotinoids exhibit much lower mammalian toxicity than traditional insecticides do, they can be enriched through routes such as food chains and drinking water to produce adverse health effects on humans. Therefore, the potential toxicity of neonicotinoids has attracted attention. However, studies focusing on related human reproductive toxicity are limited. This paper reviewed domestic and foreign studies on human neonicotinoid exposure levels, reproductive toxicity, and plausible mechanisms, aiming to suggest the possible directions for future studies.