Ki67与MRI在宫颈癌根治性手术后宫颈癌淋巴结转移中评价对比

Evaluation and Comparison of Ki67 and MRI in Lymph Node Metastasis of Cervical Cancer after Radical Operation of Cervical Cancer

目的:探究Ki67与MR在宫颈癌根治术后宫颈癌淋巴结转移中评估价值的对比。方法:选择2016年1月至2018年1月于我院接受宫颈癌根治术的151例宫颈癌患者,分别对其实施Ki67检测及MRI检测,以病理学检测结果为金标准,计算两种检测方式对宫颈癌淋巴结转移评估的准确度、敏感度、特异度、阳性预测值及阴性预测值,并进行对比分析。结果:检测评估发现,MRI对宫颈癌淋巴结转移评估准确度为31.79%,灵敏度为46.75%,特异度为16.22%,阳性预测值为36.73%,阴性预测值为22.64%。Ki67检测对宫颈癌淋巴结转移评估准确度为42.38%,灵敏度为52.56%,特异度为31.51%,阳性预测值为45.05%,阴性预测值为38.33%。两种检测方式对比显示Ki67对宫颈癌淋巴结转移具有更高的诊断准确度。结论:3相比于MRI检测,Ki67对宫颈癌淋巴结转移具有更高的诊断准确度、特异度和阴性预测值,分析其原因与MRI检测受个体因素影响更大有关。

Objective: To explore the value of Ki67 and MRI in evaluating lymph node metastasis of cervical cancer after radical operation of cervical cancer. Methods: 151 patients with cervical cancer who underwent radical operation of cervical cancer in our hospital from January 2016 to January 2018 were selected as the research objects, and Ki67 and MRI were tested respectively, and the pathological results were used as the gold standard to calculate the two methods for evaluating lymph node metastasis of cervical cancer.Accuracy, sensitivity, specificity, positive predictive value and negative predictive value were compared and analyzed. Results: Testing and evaluation found that the accuracy of MRI for cervical cancer lymph node metastasis assessment was 31.79 %, sensitivity was46.75 %, specificity was 16.22 %, positive predictive value was 36.73 %, and negative predictive value was 22.64 %. The Ki67 test has an accuracy of 42.38 %, a sensitivity of 52.56 %, a specificity of 31.51 %, a positive predictive value of 45.05 %, and a negative predictive value of 38.33 %. The comparison of the two methods showed that Ki67 had higher diagnostic accuracy for lymph node metastasis of cervical cancer. Conclusion: Compared with MRI, Ki67 had higher diagnostic accuracy, specificity and negative predictive value for lymph node metastasis of cervical cancer. Individual factors are more relevant.