甘肃汉族成人骨强度及其与体成分的关系

Bone strength and its relationship with body composition in Han adults in Gansu Province

目的探讨甘肃省不同地区汉族成人骨强度分布特点及其与体成分的关系。方法采用随机整群法,抽取甘肃省兰州市、天祝藏族自治区(天祝)、张掖肃南裕固族自治县(张掖)及临夏回族自治州(临夏)汉族成年人共2950名,用生物电阻抗体成分分析仪及超声骨密度仪测量受试者体成分指标及右足跟骨骨强度,采用多元线性回归法分析骨强度与体成分间关系。结果甘肃汉族成年男性、女性骨强度均在18~29岁达峰值,50岁后各年龄段男性骨强度均高于女性,差异有统计学意义(P<0.001);不同地区男性中,天祝县骨量异常检出率最高,兰州最低(x^2=10.772,P<0.05);女性中张掖市骨量异常检出率最高,临夏最低(x^2=35.991,P<0.001);多元线性回归分析显示,肌肉量.年龄、性别是甘肃汉族成人骨强度的影响因素(P<0.05),皮下脂肪量、内脏脂肪量与骨强度无关(P>0.05)。结论甘肃汉族成人骨强度达峰值年龄较其他部分民族偏早;不同地区汉族成人骨量异常检出率有差异,肌肉量是骨质疏松症发病的保护因素;气温等环境因素是否是骨强度的影响因素需进一步研究。

Objective To analyze the distribution of bone strength of adult Han nationalities in Gansu Province and its relationship with body composition. Methods Bioelectric impedance technique and ultrasonic bone mineral density meter were used to record the body composition and bone strength of right calcaneus of a random cluster sample with 2950 Han adults living in Lanzhou,Tianzhu,Zhangye and Linxia,Gansu Province. The association of bone strength and body composition were analyzed by using multiple linear regression. Results The peak bone strength of Han adult male and female in Gansu was reached at 18-29 years old. The bone strength of male was significantly higher than female after 50 years old( P < 0. 001). The incidence of bone mass abnormal in subjects was significantly different in different place of Gansu: Tianzhu had highest incidence in male while Lanzhou has lowest incidence( χ2= 10. 772,P < 0. 05);in female groups,the incidence was the highest in Zhangye while the lowest in Linxia( χ2= 35. 991,P < 0. 001). The result of multiple linear regression showed that,muscle mass,age and gender were related factors of bone strength of Han adults in Gansu( P < 0. 05) whereas subcutaneous fat mass and visceral fat mass were not impact factors of bone strength of Gansu Han adult( P > 0. 05). Conclusion The bone strength of Han adults in Gansu reaches its maximum earlier than some other nationalities. The incidence of bone mass abnormality is different in different places of Gansu,muscle mass is protective factors of OP. Further study is needed to test the relationship of bone strength and environmental factors( eg temperature).