比较亚洲肿瘤峰会标准与LI-RADS对乙型肝炎性小肝癌的诊断价值

Comparison on Asian Cancer Summit criteria and LI-RADS in diagnosis of hepatitis B inflammatory small hepatocellular carcinoma

目的对比分析亚洲肿瘤峰会(AOS,2016)标准与肝脏影像报告和数据系统(LI-RADS)对乙型肝炎性小肝细胞癌(sHCC)的诊断效能。方法对130例疑诊乙型肝炎性sHCC患者(共172个肝结节,直径均≤30 mm)进行上腹部CT及MR检查,以病理结果为金标准,分别计算AOS标准及LI-RADS诊断乙型肝炎性sHCC的敏感度及特异度。结果①直径≤30 mm病灶:AOS标准诊断sHCC的敏感度为55.00%(44/80),特异度92.39%(85/92);LI-RADS分级标准的敏感度100%(80/80),特异度67.39%(62/92)。②直径<20 mm病灶:AOS标准诊断的敏感度为40.00%(10/25),特异度94.34%(50/53);LI-RADS分级标准的敏感度100%(25/25),特异度71.70%(38/53)。结论对于诊断乙型肝炎性sHCC,LI-RADS标准较AOS标准的敏感度更高,有助于早期诊断及治疗。

Objective To compare Asian Oncology Summit(AOS,2016)criteria and liver imaging reporting and data system(LI-RADS)in diagnosis of hepatitis B inflammatory small hepatocellular carcinoma(sHCC).Methods Upper abdominal CT and MR examination were performed in 130 patients with suspected hepatitis B inflammatory sHCC(172 hepatic nodules with diameters≤30 mm).Taken pathological results as the gold standards,the sensitivity and specificity of AOS standard and LI-RADS for diagnosis of hepatitis B sHCC were calculated.Results①For lesions with diameter≤30 mm,the sensitivity and specificity of AOS criteria was 55.00%(44/80)and 92.39%(85/92),while of Li-RADS grading criteria was 100%(80/80)and 67.39%(62/92),respectively.②For lesions with diameter<20 mm,the sensitivity and specificity of AOS criteria was 40.00%(10/25)and 94.34%(50/53),of Li-RADS grading criteria was 100%(25/25)and 71.70%(38/53),respectively.Conclusion LI-RADS was more sensitive in diagnosis of hepatitis B inflammatory sHCC than AOS criteria,being helpful to early diagnosis and treatment.