彩色多普勒血流显像相关参数检测对孕晚期胎儿宫内生长受限的诊断及评估意义

The significance of color Doppler flow imaging in the diagnosis and evaluation of fetal intrauterine growth restriction in late pregnancy

目的:探讨彩色多普勒血流显像(CDFI)相关参数检测对孕晚期胎儿生长受限(FGR)的评估价值。方法:选取47例孕晚期胎儿FGR孕妇和同期60例健康孕晚期孕妇,孕周均34~36周,分别记为FGR组(n=47)和健康组(n=60)。彩色多普勒检测并比较两组胎儿脐动脉(UA)、大脑中动脉(MCA)和主动脉弓峡部(Aol)的血流显像相关参数差异,采用受试者工作特征(ROC)曲线分析上述血流参数指标对FGR的诊断效能。结果:FGR组胎儿头围、双顶径、腹围和股骨径均小于健康组(P<0.05);FGR组胎儿UA-PI、UA-RI、UA-S/D、Aol-ERSV均明显高于健康组(P<0.05),MCA-PI、MCA-RI、MCA-S/D和Aol-PSV/ERSV低于健康组(P<0.05);胎儿UA、MCA、Aol相关血流参数除PSV外,对FGR的诊断效能均较好,AUC 0.847~0.937,Youden指数0.69~0.87。结论:超声检测对临床诊断及评估FGR有重要价值。

Objective:To evaluate the value of color Doppler flow imaging(CDFI)in the evaluation of fetal growth restriction(FGR)in late pregnancy.Methods:47 pregnant women with FGR and 60 healthy pregnant women in the same period were selected.The gestational weeks were 34-36 weeks,which were recorded as FGR group(n=47)and healthy group(n=60).The differences of blood flow imaging parameters of fetal umbilical artery(UA),middle cerebral artery(MCA)and aortic isthmus(AOL)were detected and compared by color Doppler,ROC curve was used to analyze the diagnostic efficacy of the above blood flow parameters for FGR.Results:The fetal head circumference,biparietal diameter,abdominal circumference and femoral diameter in FGR group were smaller than those in healthy group(P<0.05).UA-PI,UA-RI,UA-S/D and Aol-ERSV were significantly higher than those of healthy group(P<0.05),and MCA-PI,MCA-RI,MCA-S/D and Aol-PSV/ERSV were lower than those of healthy group(P<0.05).Besides PSV,fetal UA,MCA,and AOL related blood flow parameters had good diagnostic efficacy for FGR,AUC 0.847~0.937,Youden index 0.69~0.87.Conclusion:The effect of ultrasonography on clinical diagnosis and evaluation of FGR is significant.