组织胶联合肾上腺素甘油果糖液在Dieulafoy病中的应用

Clinical observation of endoscopic tissue adhesive combined with epinephrine and glycerin fructose liquid in treatment of Dieulafoy disease

目的探讨组织胶联合肾上腺素甘油果糖液在胃黏膜下恒径动脉破裂出血(Dieulafoy病)中的应用效果。方法选取2018年12月—2020年2月我院收治的Dieulafoy病患者25例,均采用内镜下组织胶联合肾上腺素甘油果糖液治疗。观察患者及时止血成功率、再出血率、治疗失败或出现穿孔等并发症,转外科手术率。结果即时止血成功率为92.00%(23/25),再出血率为4.00%(1/25),转入外科手术率为8.00%(2/25)。无死亡病例,均未出现相关并发症。结论组织胶联合肾上腺素甘油果糖液治疗Dieulafoy病即时止血成功率高,再出血率及转外科手术率低,值得临床推广。

Objective To explore the application of tissue glue combined with epinephrine and fructose solution in the treatment of dieulafoy disease of gastric submucosa.Methods 25 patients with dieulafoy’s disease who admitted in the hospital from December 2018 to February 2020 were selected.All patients were treated with endoscopic tissue adhesive combined with epinephrine and glycerin fructose liquid.The success rate of timely hemostasis,rebleeding rate,treatment failure and perforation,rate of conversion to surgery in patients were observed.Results After treatment,the success rate of timely hemostasis,rebleeding rate,and the rate of conversion to surgery were 92.00%(23/25),4.00%(1/25),8.00%(2/25).There were no deaths and related complications.Conclusion Endoscopic tissue adhesive combined with epinephrine and glycerin fructose liquid in treatment of dieulafoy’s disease has high success rate of timely hemostasis,low rebleeding rate and rate of conversion to surgery,which is worthy of clinical promotion and application.