基于跨理论模型的健康教育结合抗癫痫药物对癫痫患儿血清细胞因子及自尊水平的影响

Effects of health education combined with anti-epileptic drugs on the level of serum cytokines and self-esteem in children with epilepsy based on a transtheoretical model

目的探讨基于跨理论模型的健康教育结合抗癫痫药物对癫痫患儿血清细胞因子及自尊水平的影响。方法选择我院2019年2月至10月收治的新诊断癫痫患儿74例作为研究对象,随机分为对照组和观察组各37例。两组均给予抗癫痫药物治疗,对照组给予常规健康教育,观察组增加基于跨理论模型的健康教育,连续干预3个月后,观察两组患儿血清细胞因子水平及自尊水平。结果观察组白细胞介素-2、白细胞介素-6及肿瘤细胞因子α较对照组低,差异有统计学意义(P<0.05);观察组自尊量表评分较对照组高,差异有统计学意义(P<0.05)。结论基于跨理论模型的健康教育结合抗癫痫药物可显著改善新诊断癫痫患儿的白细胞水平,降低血清细胞因子水平,提高自尊水平,对患儿早期融入社会具有非常重要的意义。

Objective To explore the effect of transtheoretical model based health education combined with antiepileptic drugs on serum cytokines and self-esteem levels in children with epilepsy.Methods A total of 74 children newly diagnosed with epilepsy who were admitted to our hospital from February to October 2019 were selected as the research subjects and were randomly divided into control group and observation group with 37 cases each.Both groups were given antiepileptic drugs;the control group was given regular health education,and the observation group was given health education based on a transtheoretical model.After continuous intervention for 3 months,the serum cytokine levels and self-esteem levels of the two groups were observed.Results The interleukin-2,interleukin-6 and tumor cytokine alpha of the observation group were lower than those of the control group,and the difference was statistically significant(P<0.05);the self-esteem scale score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Health education combined with anti-epileptic drugs based on a transtheoretical model can significantly improve the white blood cell level of children with newly diagnosed epilepsy,reduce serum cytokine levels,and improve self-esteem,which is of great significance to children′s early integration into society.