1例幽门螺杆菌感染患者17年间治疗失败原因及胃镜监测结果分析

Analysis of the H.pylori eradication failures and gastroscopic examinations in a patient with H.pylori infection for 17 years

幽门螺杆菌(Helicobacter pylori,H.pylori)是长期寄生于人体胃黏膜的微需氧型螺杆菌,是慢性胃炎、消化性溃疡、胃癌等疾病的重要致病因素。本文分析了1例H.pylori持续感染患者17年间13次根除H.pylori治疗的方法及其40次胃镜监测结果,以明确H.pylori根除失败的原因、H.pylori持续感染状态下胃黏膜内镜表现及组织病理学的动态变化。

Helicobacter pylori(H.pylori),a type of microaerophilic helicobacter,long being parasitic on human gastric mucosa,is a key pathogenic contributing factor of chronic gastritis,peptic ulcer and gastric cancer.This article reviewed the failures of H.pylori eradication after 13 treatments in a patient and studied 40 gastroscopic examinations conducted for this patient with H.pylori infection persistent over 17 years.The purpose of this study was to provide an assessment of the cause of H.pylori eradication failures,endoscopic findings,and noted dynamic changes in histopathology.