硫酸镁联合阿司匹林对子痫前期患者妊娠结局及母婴预后的影响

Influence of magnesium sulfate combined with aspirin on pregnancy outcome and maternal and infant prognosis in patients with preeclampsia

目的:探究硫酸镁联合阿司匹林对子痫前期患者妊娠结局及母婴预后的影响。方法:2018年6月-2019年10月收治子痫前期患者46例,随机分为两组,各23例。对照组采用硫酸镁治疗,观察组在硫酸镁基础上联合阿司匹林治疗,比较两组治疗效果和母婴结局。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);观察组子痫复发率、不良妊娠结局发生率和围生儿不良结局发生率均低于对照组,差异有统计学意义(P<0.05)。结论:硫酸镁联合阿司匹林治疗子痫前期效果良好,可有效改善母婴结局。

Objective:To explore the influence of magnesium sulfate combined with aspirin on pregnancy outcome and maternal and infant prognosis in patients with preeclampsia.Methods:From June 2018 to October 2019,46 patients with preeclampsia were selected and randomly divided into two groups with 23 cases in each group.The control group was treated with magnesium sulfate.The observation group was treated with aspirin on the basis of magnesium sulfate.We compared the therapeutic effect and maternal and infant outcomes between the two groups.Results:The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P<0.05).In the observation group,the recurrence rate of eclampsia,the incidence of adverse pregnancy outcomes and perinatal adverse outcomes were lower than those of the control group,the difference was statistically significant(P<0.05).Conclusion:Magnesium sulfate combined with aspirin has a good effect in the treatment of preeclampsia,which can effectively improve the maternal and infant outcomes.