基于专利信息视角探析全球CaMKⅡ相关技术研究动态

Research on Development of Global CaMKⅡ Technology Based on Patent Intelligence Analysis

钙/钙调素依赖型蛋白激酶Ⅱ(Ca2+/calmodulin-dependent protein kinase Ⅱ, CaMKⅡ)是一种多功能的丝氨酸/苏氨酸蛋白激酶,调节多种细胞生命活动,是重要的制药靶点。本文从专利信息分析的角度,利用多种可视化工具,解析全球CaMKⅡ相关专利申请趋势、地域分布、专利质量、主要专利权人、重要发明人、重点研发领域等,旨在为今后的药物研发提供启发。结果表明,CaMKⅡ相关技术研发处于稳定期。发明人呈明显聚集,组间合作较少,主要发明人特征突出。研究方向涉及心血管及神经科学等。

CaMKⅡ(Ca2+/calmodulin-dependent protein kinase Ⅱ), a multifunctional serine/threonine protein kinase, regulatecellular signal transductions. CaMKⅡ is a key target for drug discovery. From the perspective of patent information analysis, this paper analyzes the global trend of patent application, geographical distribution, patent quality, main patentees, important inventors, and research focus. This paper reveals the development trend of CaMKⅡ. Inventors cluster shows obvious aggregation, and the features of main inventors is clear. Research interests of CaMKⅡ include cardiovascular and neural science.