仙灵骨葆胶囊联合PFNA治疗老年骨质疏松患者股骨转子间骨折的疗效观察

Clinical Observation on Xianling Gubao Capsules and PFNA in the Treatment for Intertrochanteric Femoral Fracture in Elderly Patients with Osteoporosis

目的:评价仙灵骨葆胶囊联合防旋型股骨近端髓内钉(proximal femoralnail antirotation,PFNA)治疗老年骨质疏松患者股骨转子间骨折(intertrochanteric femoral fracture,IFF)的临床效果。方法:将106例患者随机分为对照组和观察组,每组53例。两组均采用PFNA内固定术治疗,观察组加服仙灵骨葆胶囊,比较两组治疗效果。结果:优良率对照组为75.47%(40/53),观察组优为92.45%(49/53),观察组高于对照组,差异有统计学意义(P<0.05)。并发症总发生率对照组为43.40%(23/53),观察组为1.88%(1/53),观察组低于对照组(P<0.05)。观察组术后疼痛缓解时间、下床活动时间及骨折愈合时间均显著低于对照组(P<0.05),而术后6个月时的髋关节骨密度明显高于对照组(P<0.05)。结论:仙灵骨葆胶囊联合PFNA治疗老年骨质疏松性IFF,可加速骨折愈合,促进髋关节功能恢复,减少并发症发生。

Objective: To assess clinical effects of Xianling Gubao capsules combined with PFNA in the treatment for intertrochanteric femoral fracture(IFF) of elderly patients with osteoporosis. Methods: All 106 patients were randomized into the control group and the observation group, 53 cases each group, both groups adopted PFNA internal fixation, and the observation group took Xianling Gubao capsules, to compare therapeutic effects between both groups. Results: The excellent rate of the control group was 75.47%(40/53), lower than 92.45%(49/53) of the observation group(P<0.05). Total incidence of the complications of the control group was 43.40%(23/53), higher than 1.88%(1/53) of the observation group(P<0.05). The observation group was lower than the control group in postoperative pain remission time, normal activity time and bone fracture healing time(P<0.05), while higher than the control group in bone mineral density of hip joint six months after the operation notably(P<0.05). Conclusion:Xianling Gubao capsules combined with PFNA could accelerate the healing of bone fracture, promote the functional recovery of hip joint and reduce the incidence of the complications in the treatment for IFF of elderly patients with osteoporosis.