摘要
棕色脂肪组织可以通过产生热量来消耗储存的化学能。棕色脂肪白色化会损害它的产热功能造成肥胖和代谢紊乱相关的疾病,减缓或抑制棕色脂肪白色化进程具有重要意义。该文综述了棕色脂肪白色化的诱导因素及关键调控因子,以期为肥胖及代谢紊乱相关疾病的预防和治疗提供新思路。
Brown adipose tissues can consume energy by generating heat.The whitening of BAT will damage its thermogenic function and cause diseases related to obesity and metabolic disorders.It is of great significance to slow down or inhibit the process of BAT whitening.This article reviews the inducing factorsand the key regulators of brown adipose tissue whitening,hoping to provide some ideas for the prevention and treatment of obesity and metabolic disorders.
作者
吴倩
王静
于亮宇
于丽秀
邓亚卉
黎维勇
WU Qian;WANG Jing;YU Liang-yu;YU Li-xiu;DENG Ya-hui;LI Wei-yong(Dept of Pharmacy,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430000,China)
出处
《中国药理学通报》
CAS
CSCD
北大核心
2021年第1期22-26,共5页
Chinese Pharmacological Bulletin
基金
国家自然科学基金资助项目(No 81573509)。
关键词
棕色脂肪组织
白色脂肪组织
棕色脂肪白色化
诱导因素
调控因子
代谢紊乱
brown adipose tissues
white adipose tissues
whitening of brown adipose tissue
inducing factor
regulators
metabolic disorders
