摘要
研究了S-型色氨酸生物合成系统的稳态优化问题.针对该问题,首先给出S-型色氨酸生物合成系统的数学模型,然后构建S-型色氨酸生物合成系统的稳态优化模型.为了求解前面构建的稳态优化问题,基于Hurwitz准则将所构建的稳态优化问题转化为新的非线性规划问题.通过计算转化后的非线性规划问题,获得了S-型色氨酸生物合成系统稳态优化问题的最优解.结果表明,与基本稳态时的色氨酸产率1.310202相比,本文获得了更高的色氨酸产率5.728457.
This paper is concerned with the steady-state optimization of S-type tryptophan biosynthesis system.Firstly,a mathematical model of S-type tryptophan biosynthesis system is given.Then a steady-state optimization model of S-type tryptophan biosynthesis system is constructed.To solve the constructed steady-state optimization problem,it is transformed to a new nonlinear programming by using the Hurwitz criterion.Solving the new problem,the optimal solution for the steady-state optimization of S-type tryptophan biosynthesis system is attained.The attained rate of tryptophan production is 5.728457,which is higher than the production rate 1.310202 at the basal steady-state.
作者
逯赫
徐恭贤
LU He;XU Gongxian(College of Mathematical Sciences,Bohai University,Jinzhou 121013,China)
出处
《渤海大学学报（自然科学版）》
CAS
2020年第2期156-159,共4页
Journal of Bohai University:Natural Science Edition
基金
国家自然科学基金项目(No:11101051)
辽宁省自然科学基金项目(No:20180550839)
辽宁省教育厅科学研究项目(No:LJ2020015)。
关键词
色氨酸生物合成
S-型系统
稳态优化
非线性规划
tryptophan biosynthesis
S-type system
steady-state optimization
nonlinear programming
