“滋肾养肝、化痰消瘀”法与脑梗死后血管新生理论探讨

Nourishing Kidney and Liver,Resolving Phlegm and Eliminating Stasis Method Promotes Angiogenesis after Cerebral Infarction

侧支循环是决定脑梗死患者预后的重要因素。脑梗死后促进血管新生对缺血神经血管单元有明确的保护作用。肝肾亏虚,痰瘀阻络为脑梗死之关键病理环节,周仲瑛教授提出"滋肾养肝、化痰消瘀",可做为脑梗死之基本治疗大法,研究证实该法能够改善脑梗死患者神经功能评分,提高生活自理能力,并促进脑梗死后血管新生,改善脑灌注。脑梗死病位在脑,根于肝肾;肝肾同源,精血互生;肾主骨生髓,脑为髓海;补益肝肾方能壮骨益髓,脑髓充养;化痰消瘀则能脉络通畅,清窍得养;故而对缺血性中风患者"滋肾养肝、化痰消瘀"法能起到滋补肝肾,填精益髓,祛瘀生新之功效。

Collateral circulation is an important prognostic factor in patients with cerebral infarction.Promoting angiogenesis after cerebral infarction has a definite protective effect on ischemic neurovascular unit.Deficiency of liver and kidney as well as phlegm and blood stasis obstruction are the key pathological links of cerebral infarction.Professor ZHOU Zhongying proposed that nourishing kidney and liver and resolving phlegm and eliminating blood stasis method can be used as the basic treatment of ischemic stroke.The research has proved that this method can improve the neurological function score and ability of self-care,promote angiogenesis and enhance the brain perfusion after cerebral infarction.Stroke is located in the brain,rooted in the liver and kidney.Liver and kidney are homologous,essence and blood are mutually generated.Kidney is the main source of bone and marrow and brain is the sea of marrow.Tonifying liver and kidney can strengthen brain marrow nourishment.Resolving phlegm and removing blood stasis can smooth the veins and clear the orifices.Therefore,for patients with ischemic stroke,"nourishing kidney and liver,resolving phlegm and eliminating blood stasis" method can play an important role in angiogenesis.