硫酸镁联合拉贝洛尔治疗妊娠期高血压的价值

The value of magnesium sulfate combined with labetalol in the treatment of hypertensive disorders complicating pregnancy

目的观察对于妊娠期高血压患者运用硫酸镁联合拉贝洛尔进行治疗的效果。方法60例妊娠期高血压患者,按照随机抽选的方式分为对照组及观察组,各30例。对照组给予硫酸镁进行治疗,观察组给予硫酸镁联合拉贝洛尔进行治疗。比较两组患者的治疗效果,治疗前后的收缩压、舒张压水平,不良妊娠结局发生情况。结果观察组患者的总有效率为96.67%(29/30),高于对照组的80.00%(24/30),差异具有统计学意义(P<0.05)。治疗前,两组患者的收缩压和舒张压比较,差异均无统计学意义(P>0.05);治疗后,观察组患者的收缩压为(132.38±4.01)mmHg(1mmHg=0.133kPa)、舒张压为(81.38±2.09)mmHg,均低于对照组的(149.38±2.07)、(88.73±3.01)mmHg,差异均具有统计学意义(P<0.05)。观察组不良妊娠结局发生率为20.00%,低于对照组的46.67%,差异具有统计学意义(P<0.05)。结论在对妊娠期高血压患者治疗的过程中给予硫酸镁、拉贝洛尔相结合的方式进行治疗,可以有效提升患者的治疗效果,帮助患者进行康复,保障产妇与胎儿健康。

Objective To observe the effect of magnesium sulfate combined with labetalol in the treatment of hypertensive disorders complicating pregnancy.Methods A total of 60 patients with hypertensive disorders complicating pregnancy were randomly divided into control group and observation group,with 30 cases in each group.The control group was treated with magnesium sulfate,and the observation group was treated with magnesium sulfate combined with labetalol.The therapeutic effect,systolic blood pressure,diastolic blood pressure before and after treatment,occurrence of adverse pregnancy outcomes were compared between the two groups.Results The total effective rate of the observation group was 96.67%(29/30),which was higher than 80.00%(24/30)of the control group,and the difference was statistically significant(P<0.05).Before treatment,there was no statistically significant difference in systolic blood pressure and diastolic blood pressure between the two groups(P>0.05).After treatment,the systolic blood pressure(132.38±4.01)mm Hg(1 mm Hg=0.133 kPa)and diastolic blood pressure(81.38±2.09)mm Hg of the observation group were all lower than(149.38±2.07)and(88.73±3.01)mm Hg of the control group,and the difference was statistically significant(P<0.05).The incidence of adverse pregnancy outcomes of the observation group was 20.00%,which was lower than 46.67%of the control group,and the difference was statistically significant(P<0.05).Conclusion In the treatment of patients with hypertensive disorders complicating pregnancy,magnesium sulfate combined with labetalol can effectively improve the treatment effect of patients,help patients recover,and protect maternal and fetal health.