期刊文献+

敏感性皮肤的发病机制 被引量:5

Pathogenesis of Sensitive Skin
下载PDF
导出
摘要 敏感性皮肤是指皮肤在生理或病理条件下发生的一种高反应状态。研究表明,敏感性皮肤的发病机制主要涉及皮肤屏障受损、神经功能失调、血管反应性增高以及免疫炎症反应等。学习敏感性皮肤的发病机制有助于指导临床精准治疗。因此,本文就国内外敏感性皮肤的发病机制作一综述。 Sensitive skin refers to the high reaction state under physiological or pathological conditions.Studies indicated that the pathogenesis of sensitive skin includes impaired skin barrier function,skin sensory nerve dysfunction,increased vascular reactivity,immune and inflammatory reactions.Learning the pathogenesis of sensitive skin can help guides clinical precision treatment.Therefore,this article reviews the pathogenesis of sensitive skin at domestic and foreign.
作者 舒鸿 何黎 SHU Hong;HE Li(Department of Dermatovenereology,the First Affiliated Hospital of Kunming Medical University,Kunming 650000,China)
出处 《皮肤科学通报》 2020年第6期555-558,M0001,共5页 Dermatology Bulletin
关键词 敏感性皮肤 发病机制 研究进展 Sensitive skin Pathogenesis Research progress
  • 相关文献

参考文献6

二级参考文献43

  • 1吴琰瑜,王学民.乳酸刺痛反应对玫瑰痤疮患者局部皮肤敏感性的评价[J].临床皮肤科杂志,2005,34(7):439-440. 被引量:14
  • 2LANE E B, MCLEAN W H. Keratins and skin disorders [ J ]. J Pathol, 2004, 204 (4) :355 -366.
  • 3DIGIOVANNA J J, BALE S J. Epidermolytic hyperkeratosis: applied molecular genetics[J]. J Invest Dermatol, 1994,102(3):390 -394.
  • 4RICHARDSON E S, LEE J B, HYDE P H, et al. A novel mutation and large size poly- morphism affecting the V2 domain of keratin 1 in an African-American family with severe, diffuse palmoplantar keratoderma of the ichthyosis hystrix Curth-Macklin type[J]. J Invest Dermatol, 2006,126( 1 ) :79 - 84.
  • 5SMITH F J D, IRVINE A D, Terron-Kwiat kowski A, et al. Loss - of = function mutations in the gene encoding filaggrin cause ichthyosis vulgaris [ J ]. Nature Genet,2006, 38,337 - 342.
  • 6PARMENTIER L, LAKHDAR H, BLANCHET-BARDON C, et al. Mapping of a second locus for lamellar ichthyosis to chromosome 2q33 - 35 [ J]. Hum Molec Genet, 1996,5:555 - 559.
  • 7ISHIDA-YAMAMOTO A. Loricrin keratoderma: a novel disease entity characterized by nuclear accumulation of mutant loricrin [J]. J Dermatol Sei, 2003,31 ( 1 ) :3 - 8.
  • 8JONKMAN M F, PASMOOIJ A M, PAS- MANS S G, et al. Loss of desmoplakin tail causes lethal acantholytic epidermolysis bullosa [J]. Am J Hum Genet, 2005,77 ( 4 ) : 653 - 660.
  • 9MITSUHIRO DENDA. Role of lipids in skin barrier function. In: Thomas Forster, ed: Cosmetic lipids and the skin barrier [ M]. NY Marcel Dekker, 2002 : 101.
  • 10CHOI MJ, MAIBACH HI. Role of ceramides in barrier function of healthy and diseased skin[J]. Am J Clin Dermatol, 2005, 6(4) :215 -223.

共引文献276

同被引文献39

引证文献5

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部