含氧杂环及其衍生物的生物降解研究进展

Research advances in biodegradation of oxygen heterocycles and their derivatives

含氧杂环化合物(Oxygenheterocycles)是污染环境中常见的一类难降解有机污染物,具有毒性和致癌特性,其所引发的环境问题受到人们广泛关注。本文综述了典型含氧单杂环化合物四氢呋喃、1,4-二氧六环以及含氧稠杂环化合物二苯并呋喃、二苯并对二噁英的生物降解研究进展,主要包括降解菌降解性能、降解途径和降解相关基因。此外,本文还对二噁英类衍生物的研究现状进行了讨论,并展望了含氧杂环及二噁英类衍生物生物降解的未来研究方向。

Oxygen heterocycles are a kind of refractory organic pollutants commonly found in polluted environments. These compounds are of immense concern from point view of the environment because they are known for their toxic and carcinogenic properties. Here, we review the research progress in the biodegradation of typical oxygen-containing monoheterocyclic compounds tetrahydrofuran, 1,4-dioxane and oxygen-containing fused heterocyclic compounds dibenzofuran and dibenzo-p-dioxin. We address the degradation performance of bacteria, the degradation pathways and degradation-related genes. In addition, we discuss the research status of dioxins, and propose further research directions of biodegradation of oxygen heterocycles and their dioxin derivatives.