立体定向放疗治疗结直肠癌肺寡转移的研究进展

Research progress of stereotactic body radiation therapy for lung oligometastases of colorectal cancer

对于结直肠癌肺寡转移的局部治疗,立体定向放疗(SBRT)与手术和射频消融术疗效相似,但适用人群更加广泛。结直肠癌肺寡转移或许具有放射抵抗性,增加剂量可以达到良好的局部控制。SBRT治疗结直肠癌肺寡转移的剂量分割和预后因素尚未确定,虽未出现严重不良反应,但仍有放射相关的不良事件发生。

Compared with surgery and radiofrequency ablation,stereotactic body radiation therapy(SBRT)has similar efficacy for local treatment of colorectal cancer with pulmonary oligometastasis,but it applies to a wide range of people.Oligometastasis of colorectal cancer may have radiation resistance,and good local control can be achieved by increasing the dose.The prescription dose and prognostic factors of SBRT in the treatment of lung oligometastasis of colorectal cancer have not been determined.There are no serious toxicities in most studies,but there are still radiation-related adverse events.