酒石酸布托啡诺用于剖宫产术后PCA中对镇痛效果和不良反应的影响

The Effect of Butorphanol Tartrate in PCA after Cesarean Section on the Analgesic Effect and Adverse Reactions

目的探讨剖宫产术后PCA中应用酒石酸布托啡诺对镇痛效果及不良反应的影响。方法收集该院2017年6月—2020年7月收治的100例剖宫产产妇作为观察样本,根据红蓝球法进行分组,其中红球的50例为对照组,PCA治疗过程中予以吗啡,蓝球的50例为研究组,PCA治疗过程中予以酒石酸布托啡诺,对两组进行镇痛效果、不良反应、镇静Ramesy评级、肛门排气时间、泌乳时间、对镇痛效果的满意度的比较。结果研究组术后2 h、4 h、24 h、48 h的VAS评分(3.52±0.34)分、(3.61±0.21)分、(2.63±0.16)分、(2.93±0.16)分与对照组(4.78±0.45)分、(4.42±0.40)分、(3.75±0.24)分、(3.32±0.24)分进行比较,研究组均低于对照组,差异有统计学意义(t=15.797、12.678、27.456、9.561,P<0.001);两组对比不良反应发生率,研究组6.00%较对照组24.00%低,差异有统计学意义(χ^2=6.353,P=0.012);研究组的镇静Ramesy评级(1.84±0.40)分优于对照组(3.02±0.63)分,肛门排气时间(20.53±3.28)h、泌乳时间(10.54±4.42)h短于对照组(22.36±4.75)h、(12.29±3.64)h,差异有统计学意义(t=11.181、2.242、2.161,P<0.05);对照组与研究组进行镇痛效果满意度的比较,研究组96.0%优于对照组80.0%,差异有统计学意义(χ^2=6.061,P=0.014)。结论酒石酸布托啡诺应用于剖宫产术后PCA中可取得良好的镇静、镇痛效果,减少不良反应,促进术后康复,提高满意度。

Objective To investigate the effect of butorphanol tartrate on analgesia and adverse reactions in PCA after cesarean section.Methods Collect 100 cesarean section paturients admitted to the hospital from June 2017 to July 2020 as observation samples,and group them according to the red-blue ball method.Among them,50 cases of red ball were the control group,and morphine was given during PCA treatment.The 50 cases of Lanqiu were the study group.Butorphanol tartrate was given during the PCA treatment.The two groups were evaluated for analgesic effect,adverse reactions,sedative Ramesy rating,anal exhaust time,lactation time,and satisfaction with the analgesic effect.Results The VAS scores of the study group were(3.52±0.34)points,(3.61±0.21)points,(2.63±0.16)points,(2.93±0.16)points and the control group(4.78±0.45)points,(4.42±0.40)points,(3.75±0.24)points,(3.32±0.24)points at 2 h,4 h,24 h,48 h after surgery,the study group was lower than the control group,and the data difference between the groups was statistically significant(t=15.797,12.678,27.456,9.561,P<0.001);the two groups compared the incidence of adverse reactions,6.00%of the study group was lower than the control group 24.00%,the difference was statistically significant(χ^2=6.353,P=0.012);the sedative Ramesy rating of the study group(1.84±0.40)points better than the control group(3.02±0.63)points,anal exhaust time(20.53±3.28)h,lactation time(10.54±4.42)h shorter than the control group(22.36±4.75)h,(12.29±3.64)h,the difference was statistically significant(t=11.181,2.242,2.161,P<0.05);the control group and the study group compared the satisfaction of the analgesic effect,the study group 96.0%was better than the control group 80.0%,the difference was statistically significant(χ^2=6.061,P=0.014).Conclusion Butorphanol tartrate used in PCA after cesarean section can achieve good sedative and analgesic effects,reduce adverse reactions,promote postoperative recovery,and improve satisfaction.It is worthy of extensive clinical application.