食物血糖应答测试方法研究进展

Review on Test Methods of Food Glycemic Responses

血糖应答是指食物对血糖水平变化的影响,能够反映食物中的碳水化合物在体内的消化代谢状态,因此食物血糖应答的测定对于糖尿病患者的膳食指导以及低血糖生成指数产品的研发过程等均有着非常重要的意义。目前最权威的测试食物血糖应答的方法是人体测试。此外,动物试验和体外消化模型由于具有简便易行、成本较低以及可大量测试食物原料等优势,也逐渐成为研究的热点。本文主要对血糖应答测试的方法包括人体测试、动物试验以及体外消化模型的研究现状进行综述,以期为后续的相关研究提供一定的指导和帮助。

Glycemic response(GR)refers to the effect of food on blood glucose fluctuation,which can reflect the digestion and metabolism of carbohydrate in the body.The determination of GR is very important for the diet guidance for diabetic patients,and the development of low glycemic index products.At present,the most authoritative method to test GR is human body test.In addition,animal test and in vitro evaluation methods have also become research focuses due to their advantages of low cost,easy operation and high throughput.This paper mainly reviews the research status of different methods on GR test including human test,animal test and in vitro digestion model,in order to provide guidance and help for the follow-up research.