经尿道前列腺等离子双极电切术治疗良性前列腺增生的有效性及安全性

Efficacy and safety of bipolar transurethral plasmakinetic resection of prostate in the treatment of benign prostatic hyperplasia

目的观察经尿道前列腺等离子双极电切术治疗良性前列腺增生(BPH)的临床效果及安全性。方法将120例BPH患者随机分为对照组和观察组,各60例。对照组采用经尿道前列腺电切术治疗,观察组采用经尿道前列腺等离子双极电切术治疗。比较两组的临床效果。结果观察组的治疗优良率高于对照组(P<0.05)。术后24 h,两组的TNF-α、hs-CRP、IL-6、PGE2、5-HT、SP水平较术前均升高,但观察组低于对照组(P<0.05)。观察组的术后并发症总发生率低于对照组(P<0.05)。结论经尿道前列腺等离子双极电切术治疗BPH的临床效果显著,可有效改善患者炎性因子水平,减轻疼痛,降低术后并发症发生率。

Objective To observe the clinical effect and safety of bipolar transurethral plasmakinetic resection of prostate in the treatment of benign prostatic hyperplasia(BPH).Methods A total of 120 patients with BPH were randomly divided into control group and observation group,with 60 cases in each group.The control group was treated with transurethral resection of prostate,and the observation group was treated with bipolar transurethral plasmakinetic resection of prostate.The clinical effects of the two groups were compared.Results The excellent and good rate of treatment in the observation group was higher than that in the control group(P<0.05).At 24 h after operation,the levels of TNF-α,hs-CRP,IL-6,PGE2,5-HT and SP in the two groups were higher than those before operation,but those in the observation group were lower than the control group(P<0.05).The total incidence of postoperative complications in the observation group was lower than that in the control group(P<0.05).Conclusion The bipolar transurethral plasmakinetic resection of prostate in the treatment of BPH has a significant clinical effect,which can effectively improve the levels of inflammatory factors,relieve pain and reduce the incidence of postoperative complications.