摘要
患者,男,61岁。全身皮肤出现色素沉着及减退斑10年余。其父、兄与其有相同的皮疹特征。皮损组织病理示:表皮角化过度,部分上皮脚融合,棘层轻度增生,真皮浅层小血管可见淋巴细胞浸润,部分真皮乳头层可见嗜伊红团块状物质,其间可见裂隙。真皮乳头层团块状物质刚果红染色阳性。结合临床及实验室检查,诊断为色素异常性皮肤淀粉样变病。
A 61-year-old male presented with brownish reticulate pigmentation with hypopigmented and hyperpigmented macules all over the body for more than ten years.His father and elder brother share the same skin characteristics.The skin biopsy of the lesion showed epidermal hyperkeratosis and acanthosis,accompanied by perivascular lymphocytic infiltration in the superficial dermis.Eosinophilic clumps can be found in the dermal papilla.Additionally,Congo red stain in dermal papilla was positive.The diagnosis of amyloidosis cutis dyschromica was made according to the clinical manifestation and laboratory results.
作者
徐欣植
吴杰
杨骥
李明
XU Xinzhi;WU Jie;YANG Ji;LI Ming(Department of Dermatology,Zhongshan Hospital of Fudan University,Shanghai 200032,China)
出处
《中国麻风皮肤病杂志》
2021年第1期40-42,共3页
China Journal of Leprosy and Skin Diseases
