补肝益肾汤联合渐进式腰背肌功能锻炼对骨质疏松性椎体压缩骨折患者疼痛及骨密度的影响

Effect of Bugan Yishen Decoction Combined with Progressive Functional Exercise of Low Back Muscles on Pain and Bone Density in Patients with Osteoporotic Vertebral Compression Fractures

目的:观察补肝益肾汤联合渐进式腰背肌功能锻炼对骨质疏松性椎体压缩骨折患者疼痛、骨密度的影响并探讨其机制。方法:选取甘肃中医药大学第一附属医院2017年1月至2019年1月治疗的骨质疏松性椎体压缩骨折患者60例,随机分为观察组和对照组各30例,对照组给予口服补肝益肾汤配合卧床休息;观察组在口服补肝益肾汤的基础上联合渐进式腰背肌功能锻炼,1周为1个疗程,分别观察两组患者治疗前、治疗后1个疗程、2个疗程、3个疗程的视觉模拟量表(VAS)评分、Oswestry功能障碍指数(ODI)评分及骨密度值。结果:治疗前两组患者VAS评分、ODI评分及骨密度值比较差异无统计学意义(P>0.05),治疗后两组患者不同时间点VAS评分、ODI评分均较治疗前下降,且随着疗程的增加呈持续性降低(P<0.05);组间比较,观察组在各相应时间点的VAS评分、ODI评分均低于对照组(P<0.05)。治疗后两组患者骨密度值均较治疗前改善(P<0.05),组间比较,治疗后观察组较对照组骨密度测定值改善更明显(P<0.05)。结论:采用肝补益肾汤联合渐进式腰背肌功能锻炼能够明显提高骨质疏松性椎体压缩骨折患者的生活质量及骨密度值,且在改善疼痛方面具有明显的优势。

Objective:To observe the effect of bugan yishen decoction combined with progressive lumbar and back muscle functional exercise on pain and bone density in patients with osteoporotic vertebral compression fractures and to explore its mechanism.Methods:60 patients with osteoporotic vertebral compression fractures treated in our hospital from January 2017 to January 2019 were randomly divided into the observation group and the control group of 30 cases each.The control group was given oral bugan yishen decoction in conjunction with bed rest.The observation group was given bugan yishen decoction combined with progressive lumbar and back muscle functional exercise,1 week as a course of treatment,and the VAS score,ODI score and bone mineral density of the two groups of patients before the treatment,1 course,2 courses,3 courses after the treatment were observed.Results:The VAS score,ODI score and bone density value of the two groups of patients before treatment were not statistically different(P>0.05).After treatment,the VAS score and ODI score of the two groups of patients at different time points were significantly lower than that before treatment,and with the increase of the course of treatment,it showed a continuous decrease(P<0.05).Compared between the two groups,the VAS score and ODI score of the observation group at each corresponding time point were significantly lower than that of the control group(P<0.05).After treatment,the bone mineral density values of the two groups were improved compared with those before treatment(P<0.05),and the bone mineral density values of the observation group after the treatment was better than that of the control group(P<0.05).Conclusion:The treatment of bugan yishen decoction combined with functional exercises of the lumbar and back muscles can significantly improve the quality of life and bone mineral density of patients with osteoporotic vertebral compression fractures,and it has obvious advantages in improving pain.