摘要
目的银杏作为常见的中草药在我国有着悠久的药用历史。银杏黄酮是银杏叶中提取的最主要有效药用成分之一。根据银杏黄酮的理化性质可以通过树脂吸附法、超临界萃取法和溶剂法等方法对其进行分离纯化。研究发现银杏黄酮具有促血液循环、抗氧化、抗衰老、提升记忆力、抗肿瘤和肝保护等药理作用,临床上已经用于治疗心绞痛、冠心病、心肌缺血、高血压、高血脂、糖尿病、阿尔兹海默症、动脉粥样硬化、胃癌和卵巢恶性肿瘤等疑难杂症。
Ginkgo biloba as a traditional Chinese herb has a long medicinal history in China. Ginkgo flavone is one of the most effective medicinal components extracted from ginkgo leaf. According to the physical and chemical properties of ginkgo flavone,it can be separated and purified by resin adsorption,supercritical fluid extraction and solvent extraction. Previous studies have proved that ginkgoflavonepossesses pharmacological effects in promoting blood circulation,anti-oxidation,anti-aging,improving memory,anti-tumor and liver protection and so on. Ginkgo flavone has been used clinically to treat angina pectoris,coronary heart disease,myocardial ischemia,hypertension,hyperlipidemia,diabetes,alzheimers disease,atherosclerosis,gastric cancer and ovarian malignancy and other difficult miscellaneous diseases.
作者
权明春
苏振宏
方大维
谢小林
解举民
QUAN Mingchun;SU Zhenhong;FANG Dawei;XIE Xiaolin;XIE Jumin(Medical Cllege of Hubei Polytechnic University,Huangshi,Hubei 435003,China;Hubei Key Laboratory of Renal Disease Occurrence and Intervention,Hubei Polyechnic University,Huangshi,Hubei 435003,China;General Surgery Department,The Second People's Hospial of Huangshi,Huangshi,Hubei 435000,China;Department of Medical,Huangshi Psychiatric Hospital,Huangshi,Hubei 435003,China)
出处
《今日药学》
CAS
2020年第11期789-792,共4页
Pharmacy Today
基金
湖北省自然科学基金(2018CFB406)
湖北理工学院人才引进项目(19XJK02R)。
关键词
银杏黄酮
药理作用
分离纯化
疾病治疗
Ginkgo flavone
pharmacological functions
separation and purification
disease treatment
