孟鲁司特钠用于咳嗽变异性哮喘治疗的效果

Effect of Montelukast Sodium on Cough Variant Asthma Treatment

目的对咳嗽变异性哮喘患者应用孟鲁司特钠治疗的效果进行观察。方法选择我院收治的咳嗽变异性哮喘患儿70例作为研究对象,选取时间段为2018年4月—2019年5月,按照其病历单双号将其划分为雾化组和联合组,每组各有35例。采用布地奈德雾化的方式对雾化组患儿予以治疗,在此基础上,采用孟鲁司特钠对联合组予以治疗,对比两组的治疗效果。结果联合组达到了94.3%的治疗有效率,雾化组达到了77.1%的治疗有效率,联合组患儿的治疗有效率明显高于雾化组,两组患儿比较差异有统计学意义(P<0.05)。联合组的症状缓解时间和症状消失时间均明显低于雾化组,两组患儿比较差异有统计学意义(P<0.05)。结论针对咳嗽变异性哮喘患儿采用孟鲁司特钠进行治疗具有显著的临床疗效,而且能够有效改善患儿的临床症状。

Objective To observe the effect of montelukast sodium in patients with cough variant asthma.Methods Seventy children with cough variant asthma admitted in our hospital were selected as the research object,and the time period was selected from April 2018 to May 2019.According to their medical records,they were divided into nebulized group and combined group.There were 35 cases in each group.The children in the nebulized group were treated with budesonide nebulization.On this basis,the montelukast sodium was used to treat the combined group,and the therapeutic effects of the two groups were compared.Results The combined group achieved a therapeutic efficiency of 94.3%,and the nebulized group achieved a therapeutic efficiency of 77.1%.The combined effective rate of the children in the combined group was significantly higher than that of the nebulized group.The comparison between the two groups of children was statistically tested(P<0.05).The symptom relief time and symptom disappearance time of the combined group were significantly lower than those of the nebulized group,and the children in the two groups were statistically tested(P<0.05).Conclusion The treatment of children with cough variant asthma using Montelukast sodium has significant clinical efficacy and can effectively improve the clinical symptoms of children.