维生素D对多囊卵巢综合征患者促排卵的临床研究

Clinical Study of Vitamin D on Ovulation of Patients with Polycystic Ovary Syndrome

目的分析维生素D对多囊卵巢综合征患者促排卵的临床影响。方法选取2019年4月至2019年12月本院接诊的70例多囊卵巢综合征患者为研究对象,采用随机数表法将患者分为对照组(n=35)和试验组(n=35)。给予对照组患者常规屈螺酮炔雌醇片进行治疗,试验组患者在此基础上增加维生素D治疗,对比两组患者治疗前后的维生素D水平、激素水平、治疗半年后妊娠率和预后满意度。结果试验组维生素D水平、激素水平与对照组比较,明显改善,试验组治疗半年后的妊娠率较对照组更高,患者的预后满意度较对照组更高,差异具有统计学意义(P<0.05)。结论多囊卵巢综合征患者常伴有维生素D缺乏的症状,在促排卵的治疗过程中补充维生素D,能够优化患者的激素水平,提高患者的妊娠率。

Objective To explore and analyze the clinical effect of vitamin D on ovulation of patients with polycystic ovary syndrome.Methods A total of 70 patients with polycystic ovary syndrome treated in our hospital from April 2019 to December 2019 were selected as subjects,and all patients were divided into control group(35 cases)and experimental group(35 cases)by random number table method.Patients in the control group were given conventional ethinylestradiol cyprogesterone for treatment,while patients in the experimental group were given vitamin D treatment on the basis of this medication.Vitamin D levels,hormone levels,pregnancy rate and prognosis satisfactions of patients between the two groups were compared before and after treatment.Results Compared with the control group,the vitamin D level and hormone level of the patients in the experimental group were significantly improved.The pregnancy rate of the experimental group was higher than that of the control group after six months of treatment,and the prognosis satisfaction of the patients was higher than that of the control group,with statistically significant differences(P<0.05).Conclusion Patients with polycystic ovary syndrome are often accompanied by the symptoms of vitamin D deficiency.Supplementation of vitamin D during the treatment of ovulation induction can optimize the hormone levels of patients and improve the pregnancy rate of patients.