职业性汽油接触与代谢综合征关系研究

Investigation of the relationship between occupational gasoline exposure and metabolic syndrome

目的探讨职业性汽油接触与代谢综合征(MS)的关系。方法于2019年9月,采用整群抽样的方法,以北京市某石油销售公司147名职业性汽油接触人员为观察组,以该公司158名无职业性汽油接触人员为对照组,通过职业健康检查获得体重指数(BMI)、血压(收缩压、舒张压)和空腹血糖(FPG)、甘油三酯(TG)和高密度脂蛋白胆固醇(HDL-C)等数据,并分析研究对象的一般人口学特征、职业史、既往史、个人史。结果与对照组比较,观察组人群收缩压、舒张压、FPG、TG、BMI水平以及MS、肥胖、高血压检出率均较高,差异均有统计学意义(P<0.05);与对照组比较,观察组年龄、性别、工龄、饮酒、吸烟、婚姻状态、HDL-C水平、TG升高和HDL-C偏低检出率差异均无统计学意义(P>0.05)。观察组发生MS的危险是对照组的1.988倍(P<0.05)。结论职业性汽油接触可能导致MS检出率升高。

Objective To explore the correlation between occupational gasoline exposure and metabolic syndrome(MS).Methods In September 2019,a total of 147 occupational gasoline exposure workers from a oil sales company in Beijing were selected as the observation group by using cluster sampling method,158 people without gasoline exposure from the company were selected as the control group.Occupational health examination were performed to measure body mass,blood pressure and fasting plasma glucose(FPG),triglycerides(TG),high-density lipoprotein cholesterol(HDL-C)and other data.General demographic characteristics,occupational history,past medical history and personal history were analyzed either.Results The levels of systolic blood pressure,diastolic blood pressure,FPG,TG and BMI in the observation group were all higher than those in the control group(P<0.05).The detection rates of MS,obesity and hypertension in the observation group were all higher than those in the control group(P<0.05).There were no significant differences in age,gender,working age,drinking,smoking,marital status,HDL-C level,detection rates of abnormal TG and HDL-C between the observation group and the control group(P>0.05).The odds ratio(OR)of MS in the observation group was 1.988 times that in the control group(P<0.05).Conclusion Occupational gasoline exposure is associated with the increasing detection rate of MS.