中国老年骨科住院患者医院感染危险因素荟萃分析

Meta-analysis of Risk Factors for Nosocomial Infection in Elderly Orthopaedic Inpatients in China

目的:分析老年骨科住院患者医院感染危险因素,为制订医院感染管理策略提供依据。方法:计算机检索中国知网(CNKI)、万方数据(Wanfang data)、维普(CQVIP)、中国生物医学文献数据库(CBM)、PubMed及Embase数据库中老年骨科住院患者医院感染相关文献,提取数据进行荟萃分析。结果:共纳入32篇文献,包括老年骨科住院患者20 672例,其中医院感染1 943例。荟萃分析结果显示,年龄>70岁[OR=2.09,95%CI(1.47,2.97)]、患有基础疾病[OR=3.44,95%CI(2.58,4.59)]、进行侵入性操作[OR=3.21,95%CI(2.14,4.80)]是老年骨科住院患者医院感染危险因素。结论:高龄、患有基础疾病及侵入性操作等均为老年骨科患者发生医院感染的危险因素。

Objective:To evaluate the risk factors for nosocomial infection in elderly orthopaedic inpatients,and to provide basis for formulating nosocomial infection management strategy.Method:The CNKI,Wanfang Data,CQVIP,CBM,PubMed and Embase databases were searched by computer for the related literatures of nosocomial infection in elderly orthopedic inpatients,and extracted the data for meta-analysis.Result:A total of 32 literatures were included,including 20 672 elderly orthopaedic inpatients,including 1 943 cases of nosocomial infection.The results of meta-analysis showed that age >70 years old[OR=2.09,95%CI (1.47,2.97)],basic disease[OR=3.44,95%CI (2.58,4.59)],invasive procedures[OR=3.21,95%CI (2.14,4.80)]were risk factors for nosocomial infection in elderly orthopaedic inpatients.Conclusion:Old age,basic diseases and invasive procedures are all risk factors for nosocomial infection in elderly orthopaedic patients.