改善胰岛素抵抗的中药活性成分及作用机制研究进展

Study Progress on Active Ingredients of Chinese Materia Medica and Their Mechanism to Improve Insulin Resistance

近五年来,共发现能改善胰岛素抵抗的中药活性成分35种。全面概述了这35种成分的来源、理化性质、分子结构。它们通过调控不同信号通路发挥改善胰岛素抵抗作用,机制主要包括抑制氧化应激、抵抗炎症反应、调控葡萄糖转运通路、促进脂肪酸分解。参考文献50篇。

In the past five years,scholars in the field of Chinese materia medica have found 35 kinds of active ingredients that can improve insulin resistance.This article provides a comprehensive overview of the origin,physical and chemical properties,and molecular structure of these 35 components.They play a role in improving insulin resistance by regulating different signaling pathways.The main mechanism involves inhibiting oxidative stress,resisting inflammatory responses,regulating glucose transport pathway,and promoting the decomposition of fatty acids.There are 50 references.