摘要
海藻共附生真菌次级代谢产物结构类型多样、骨架新颖、活性丰富,为新型海洋药物先导化合物的发现提供了宝贵的来源。本文以生物活性对海藻共附生真菌来源的天然产物进行分类,从抗菌、抗肿瘤、抗氧化、抗炎、浮游生物抑制等方面,对2006年以来报道的海藻共附生真菌来源的112个活性天然产物进行概述,为海藻及其共附生微生物的进一步研究与开发提供参考。
The secondary metabolites from marine alga-derived possess diverse structure types,novel skeletons and abundant activities,and provide a valuable source for the screening and discovery of new marine drug lead compounds.In this paper,we classify natural products from marine alga-derived fungi according to the types of biological activities.From the aspects of antibacterial,anti-tumor,antioxidant,anti-inflammatory,plankton inhibition,etc.,112 activities from marine alga-derived fungi reported in 2006 are summarized,which provides references for further research of marine alga and marine alga-derived microorganisms.
作者
杨曦亮
王健娇
姜睿
刘永宏
周雪峰
YANG Xiliang;WANG Jianjiao;JIANG Rui;LIU Yonghong;ZHOU Xuefeng(Medical College,Wuhan University of Science of Technology,Wuhan,Hubei,430081,China;Guangdong Key Laboratory of Marine Materia Medica,South China Sea Institute of Oceanology,Chinese Academy of Sciences,Guangzhou,Guangdong,510301,China)
出处
《广西科学》
CAS
2020年第5期462-474,共13页
Guangxi Sciences
基金
国家自然科学基金项目(31900286,81973235,21977102)
广东省自然科学基金杰出青年项目(2019B151502042)资助。
关键词
海藻共附生真菌
次级代谢产物
天然产物
生物活性
海洋药物
alga derived fungi
secondary metabolites
natural products
biological activities
marine drugs